Activity Title

The ADVENT-HF Trial

Statement of Need/Program Overview

This educational activity is designed to review, in detail, the results of the ADVENT-HF randomized clinical trial. The effects of a particular type of adaptive servo-ventilation, triggered by changes in peak-flow (ASVPF), on obstructive and central sleep apnea (OSA and CSA, respectively) in patients with heart failure and reduced ejection fraction (HFrEF) will be presented. The focus will be on the effects of ASVPF reduced on cardiovascular morbidity as well as on sleep structure and health-related quality of life. The implications of these findings for clinical management of both OSA and CSA in patients with HFrEF will be reviewed.

Target Audience

This activity is intended for medical professionals who have a clinical interest in the management of respiratory patients as seen by the following medical specialists: Pulmonologists, Pneumologists, Respirologists, Respiratory Physiotherapists, Respiratory Therapists (Hospital, Home), Thoracic Surgeons, Home Healthcare Providers, Critical Care Medicine Specialists, Internal Medicine Specialists, Primary Care Physicians (General and Family Practitioners), Advanced Practice Nurses, Nurse Practitioners, Physicians Assistants, Managed Care Medical Directors, and other Practitioners and Payers.

Educational Objectives

After completing this activity, the participant should be better able to:

1. Examine the necessary elements in lab polysomnogram, and clinical assessment of patients with
   heart failure and sleep apnea.
2.  Describe the management of sleep apnea in heart failure according to phenotype of sleep apnea
   and heart failure.
3.  Describe how the results of the ADVENT-HF trial may change the management of heart failure
   patients with reduced ejection fraction and sleep apnea.
4.  Analyze the impact of the ADVENT-HF study findings on clinical practice by validating the
   inference that the high prevalence of obstructive sleep apnea (OSA) and central sleep apnea
   (CSA) in patients with heart failure with reduced ejection fraction (HFrEF) supports a lower
   threshold for performing diagnostic sleep studies.
5.  Identify which monitoring devices should be avoided as they do not reliably distinguish OSA
   from CSA.
6.  Explain the discrepancies between randomized trial results and epidemiological data regarding
   the treatment of OSA and CSA with Adaptive Servo-Ventilation with Positive Pressure Flow in
   patients with HFrEF.
7. Identify best practices for treating patients with heart failure with HFrEF and coexisting OSA and
   CSA based on the ADVENT-HF study findings.

Faculty

Prof. Dr. med. Michael Arzt
Professor of Internal Medicine, Sleep and Ventilation
Centre of Sleep Medicine
Department of Internal Medicine II
University Hospital Regensburg
Regensburg, Germany

T. Douglas Bradley, MD
Professor of Medicine
University Health Network Toronto General Hospital
Department of Medicine, Division of Respirology
Toronto, ON, Canada

Program Agenda

Educational Presentation (2 hours 15 minutes)
Post Test and Evaluation (5 minutes)
Total Activity: (2 hours 20 minutes)

European Accreditation Council for Continuing Medical Education (EACCME)

EACCME Accreditation Statement

The ADVENT-HF Trial, made available and organized by Dane Garvin Ltd., is accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) to provide the following CME activity for medical specialists. Only those e-learning materials that are displayed on the UEMS-EACCME® website have formally been accredited.

EACCME Term Offering

January 24, 2025 to January 24, 2027 

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 Credits^TM . Information on the process to convert EACCME® credit to AMA credit can be found at https://edhub.ama-assn.org/pages/applications.

Information regarding the conversion of EACCME® credits
Credit will be converted based on one (1) hour of participation equalling one credit for all activities. Physicians wishing to convert EACCME® credits to AMA PRA Category 1 Credit™ will be required to access the AMA website at https://edhub.ama-assn.org/pages/applications to obtain the necessary paperwork and instructions. Physicians and other health care professionals will be required to pay a processing fee to the AMA.

For other countries, please contact the relevant national/regional accreditation authority.

American Association for Respiratory Care (AARC) Accreditation

AARC Designation Statement
This Non-traditional program has been approved for 2.25 contact hour Continuing Respiratory Care Education (CRCE) credit by the American Association for Respiratory Care; 9425 N. MacArthur Boulevard, Suite 100, Irving TX 75063

How to Obtain AARC / CRCE Credit

Attendees are expected to review all academic materials before attempting to apply for credit. Successful completion of this activity will lead to the issuance of a certificate for 2.25 contact hour of CRCE approved continuing education.

To receive credit, please follow these steps:

• Complete the online registration (registration is free).
• Review all of the academic materials provided.
• Click on the CRCE link to apply for credit.
• Complete the online test and/or evaluation. Participants must receive a test score of at least 70% and answer all evaluation questions to receive a certificate.
• Qualified applicants will be provided with an online (printable) CRCE certificate based on their attendance and satisfactory completion of this academic activity.

Term Offering - AARC / CRCE

This activity was released on February 2, 2025 and is valid for two years. Requests for credit must be made no later than February 2, 2027.

Other Allied Healthcare Professional

Participation Statement
Dane Garvin Ltd. has awarded 1.0 Participation Credit(s) for qualified attendees in the enduring activity The ADVENT-HF Trial.

Educational Grant

This educational activity is independently produced and is financially supported with an unrestricted educational grant by Philips Respironics.

Copyright

Copyright^© Dane Garvin Ltd. All Rights Reserved. Permission for use granted to accreditation providers.

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